# Supported Machines ```{raw} html ``` ## Liquid Handling ### Liquid Handling Workstations | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | Hamilton | STAR(let) | arm | Full | {doc}`PLR <00_liquid-handling/hamilton-star/_hamilton-star>` / [OEM](https://www.hamiltoncompany.com/microlab-star) | | Hamilton | Vantage | arm | Mostly | {doc}`PLR <00_liquid-handling/hamilton-vantage/_hamilton-vantage>` / [OEM](https://www.hamiltoncompany.com/microlab-vantage) | | Hamilton | Prep | | WIP | [OEM](https://www.hamiltoncompany.com/microlab-prep) | | Hamilton | Nimbus | arm | Mostly | [OEM](https://www.hamiltoncompany.com/microlab-nimbus) | | Tecan | EVO | arm | Basic | {doc}`PLR <00_liquid-handling/tecan-evo/_tecan-evo>` / [OEM](https://lifesciences.tecan.com/freedom-evo-platform) | | Opentrons | OT-2 | | Mostly | {doc}`PLR <00_liquid-handling/opentrons/ot2/hello-world>` / [OEM](https://opentrons.com/products/ot-2-robot) | ### Pumps | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Cole Parmer | Masterflex L/S 07522-20 07522-30 07551-20 07551-30 07575-30 07575-40 | Full | {doc}`PLR <00_liquid-handling/pumps/cole-parmer-masterflex>` / [OEM](https://www.masterflex.nl/assets/uploads/2017/09/07551-xx.pdf) | | Agrowtek | Pump Array | Full | [OEM](https://www.agrowtek.com/index.php/products/dosing_systems/dosing-pumps/agrowdose-adi-digital-persitaltic-dosing-pumps-detail) | ### Plate Washers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Agilent (BioTek) | EL406 | Mostly | {doc}`PLR <00_liquid-handling/plate-washing/biotek-el406>` / [OEM](https://www.agilent.com/en/product/microplate-instrumentation/microplate-washers-dispensers/biotek-el406-washer-dispenser-795212) | | Agilent (BioTek) | EL405 | Mostly | [OEM](https://www.agilent.com/en/product/microplate-instrumentation/microplate-washers-dispensers/biotek-elx405-select-deep-well-microplate-washer-1623186) | ### Bulk Dispensers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Thermo Fisher Scientific | Multidrop Combi | Mostly (v1b1) | [OEM](https://www.thermofisher.com/order/catalog/product/5840300) | | Formulatrix | Mantis | WIP | [OEM](https://formulatrix.com/liquid-handling-systems/mantis-liquid-handler/) | --- ## Material Handling ### Arms | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Brooks Automation | PreciseFlex PF400 | Full | {doc}`PLR <01_material-handling/arms/c_scara/precise-flex-pf400/hello-world>` / [OEM](https://www.brooks.com/laboratory-automation/collaborative-robots/preciseflex-400/) | | Brooks Automation | PreciseFlex PF3400 | Full | {doc}`PLR <01_material-handling/arms/c_scara/precise-flex-pf400/hello-world>` / [OEM](https://www.brooks.com/laboratory-automation/collaborative-robots/preciseflex-400/) | | PAA | KX2 | Mostly | | | UFactory | xArm 6 | Basics (v1b1) | [OEM](https://www.ufactory.cc/xarm-collaborative-robot/) | ### Centrifuges | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Agilent | VSpin | Mostly | {doc}`PLR <01_material-handling/centrifuge/agilent_vspin>` / [OEM](https://www.agilent.com/en/product/automated-liquid-handling/automated-microplate-management/microplate-centrifuge) | | Agilent | VSpin Access2 Loader | Full | [PLR](01_material-handling/centrifuge/agilent_vspin.ipynb#loader) / [OEM](https://www.agilent.com/en/product/automated-liquid-handling/automated-microplate-management/microplate-centrifuge) | | Hettich | SBS 300 R | WIP | [OEM](https://www.hettweb.com/products/sbs300robotic/) | | Hettich | ROTANTA 460 Robotic | WIP | [OEM](https://www.hettichlab.com/) | | Hettich | Other Generation 2 robotic centrifuges | WIP | [OEM](https://www.hettichlab.com/) | ### Fans | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | Hamilton | HEPA Fan | air filtration | Full | {doc}`PLR <01_material-handling/fans/fans>` | ### Heater Shakers | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | Inheco | Thermoshake RM | heating | Full | {doc}`PLR <01_material-handling/heating_shaking/inheco>` / [OEM](https://www.inheco.com/thermoshake-classic.html) | | Inheco | Thermoshake | heatingactive cooling | Full | {doc}`PLR <01_material-handling/heating_shaking/inheco>` / [OEM](https://www.inheco.com/thermoshake.html) | | Inheco | Thermoshake AC | heatingactive cooling | Full | {doc}`PLR <01_material-handling/heating_shaking/inheco>` / [OEM](https://www.inheco.com/thermoshake-ac.html) | | Opentrons | Thermoshake | heating | Full | [OEM](https://opentrons.com/products/heater-shaker-module) | | Hamilton | Heater Shaker | heating | Full | {doc}`PLR <01_material-handling/heating_shaking/hamilton>` / [OEM](https://www.hamiltoncompany.com/temperature-control/hamilton-heater-shaker) | | QInstruments | BioShake | heatingactive cooling | Full | {doc}`PLR <01_material-handling/heating_shaking/qinstruments>` / [OEM](https://www.qinstruments.com/automation/) | ### Storage | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | Thermo Fisher Scientific | Cytomat 6000 | heating | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / [OEM](https://assets.thermofisher.com/TFS-Assets/CMD/brochures/br-90468-cytomat-2-c-lin-br90468-en.pdf) | | Thermo Fisher Scientific | Cytomat 6002 | heating | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / [OEM](https://www.thermofisher.com/order/catalog/product/50075279) | | Thermo Fisher Scientific | Cytomat 2 C_50 | heating | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / OEM? | | Thermo Fisher Scientific | Cytomat 2 C425 | heatingactive cooling | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / [OEM](https://www.thermofisher.com/order/catalog/product/51033032) | | Thermo Fisher Scientific | Cytomat 2 C450_SHAKE | heatingshaking | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / [OEM](https://www.thermofisher.com/order/catalog/product/51033035) | | Thermo Fisher Scientific | Cytomat 5C | heating | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / [OEM](https://www.thermofisher.com/order/catalog/product/51031526) | | Thermo/Liconic | Heraeus Cytomat | heating | Full | {doc}`PLR <01_material-handling/storage/cytomat>` / OEM? | | Inheco | Incubator Shaker (MTP/DWP) | heatingshaking | Mostly | [OEM](https://www.inheco.com/incubator-shaker.html) | | Inheco | SCILA | heatingshaking | Mostly | [OEM](https://www.inheco.com/scila.html) | | Liconic | STX series | heatingactive cooling | Mostly | {doc}`PLR <01_material-handling/storage/liconic>` / [OEM](https://www.liconic.com/stx.html) | ### Peelers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Azenta Life Sciences | XPeel | Full | [OEM](https://www.azenta.com/products/automated-plate-seal-remover-formerly-xpeel) | ### Sealers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Azenta Life Sciences | a4S | Full | {doc}`PLR <01_material-handling/sealers/a4s>` / [OEM](https://www.azenta.com/products/automated-roll-heat-sealer-formerly-a4s) | ### Thermocyclers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Opentrons | Thermocycler | Full | [OEM](https://opentrons.com/products/thermocycler-module-1) | | Thermo Fisher Scientific | ATC | Full | [OEM](https://www.thermofisher.com/us/en/home/life-science/pcr/thermal-cyclers-realtime-instruments/thermal-cyclers/automated-thermal-cycler-atc.html) | | Thermo Fisher Scientific | ProFlex | Full | [OEM](https://www.thermofisher.com/us/en/home/life-science/pcr/thermal-cyclers-realtime-instruments/thermal-cyclers/proflex-pcr-system.html) | | Inheco | ODTC | Mostly | [OEM](https://www.inheco.com/odtc.html) | ### Temperature Controllers | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | Opentrons | Temperature Module | heatingactive cooling | Mostly | {doc}`PLR <01_material-handling/temperature-controllers/ot-temperature-controller>` / [OEM](https://opentrons.com/products/temperature-module-gen2) | | Inheco | CPAC | heatingactive cooling | Full | [OEM](https://www.inheco.com/cpac.html) | | Hamilton | Heater/Cooler | heatingactive cooling | Full (v1b1) | [OEM](https://www.hamiltoncompany.com/temperature-control/hamilton-heater-cooler) | ### Tilting | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Hamilton | Tilt Module | Full | {doc}`PLR <01_material-handling/tilting>` / [OEM](https://www.hamiltoncompany.com/other-robotics/188061) | --- ## Analytical Machines ### Plate Readers | Manufacturer | Machine | Features | PLR-Support | Links | |--------------|---------|----------|-------------|--------| | BMG Labtech | CLARIOstar (Plus) | absorbancefluorescenceluminescence | Full | {doc}`PLR <02_analytical/plate-reading/bmg-clariostar>` / [OEM](https://www.bmglabtech.com/en/clariostar-plus/) | | Agilent (BioTek) | Cytation 1 | absorbancefluorescenceluminescencemicroscopy | Full | {doc}`PLR <02_analytical/plate-reading/cytation>` / [OEM](https://www.agilent.com/en/product/cell-analysis/cell-imaging-microscopy/cell-imaging-multimode-readers/biotek-cytation-1-cell-imaging-multimode-reader-1623200) | | Agilent (BioTek) | Cytation 5 | absorbancefluorescenceluminescencemicroscopy | Full | {doc}`PLR <02_analytical/plate-reading/cytation>` / [OEM](https://www.agilent.com/en/product/cell-analysis/cell-imaging-microscopy/cell-imaging-multimode-readers/biotek-cytation-5-cell-imaging-multimode-reader-1623202) | | Agilent (BioTek) | Synergy H1 | absorbancefluorescenceluminescence | Full | {doc}`PLR <02_analytical/plate-reading/synergyh1>` / [OEM](https://www.agilent.com/en/product/microplate-instrumentation/microplate-readers/multimode-microplate-readers/biotek-synergy-h1-multimode-reader-1623193) | | Agilent (BioTek) | Synergy HT | absorbancefluorescenceluminescence | Full | [OEM](https://www.agilent.com/en/product/microplate-instrumentation/microplate-readers/multimode-microplate-readers/biotek-synergy-ht-multi-mode-reader-1623194) | | Byonoy | Absorbance 96 Automate | absorbance | Full | {doc}`PLR <02_analytical/plate-reading/byonoy/absorbance>` / [OEM](https://byonoy.com/absorbance-automate/) | | Byonoy | Luminescence 96 | luminescence | Full | {doc}`PLR <02_analytical/plate-reading/byonoy/luminescence>` / [OEM](https://byonoy.com/luminescence-96/) | | Byonoy | Luminescence 96 Automate | luminescence | Full | {doc}`PLR <02_analytical/plate-reading/byonoy/luminescence>` / [OEM](https://byonoy.com/luminescence-96-automate/) | | Molecular Devices | SpectraMax M5e | absorbancefluorescence time-resolved fluorescencefluorescence polarization | Full | [OEM](https://www.moleculardevices.com/products/microplate-readers/multi-mode-readers/spectramax-m-series-readers) | | Molecular Devices | SpectraMax 384plus | absorbance | Full | [OEM](https://www.moleculardevices.com/products/microplate-readers/absorbance-readers/spectramax-abs-plate-readers) | | Molecular Devices | ImageXpress Pico | microscopy | Basics | {doc}`PLR <02_analytical/plate-reading/pico>` / [OEM](https://www.moleculardevices.com/products/cellular-imaging-systems/high-content-imaging/imagexpress-pico) | | Molecular Devices | ImageXpress Micro | microscopy | WIP | [OEM](https://www.moleculardevices.com/products/cellular-imaging-systems/high-content-imaging/imagexpress-micro-4) | | Molecular Devices | ImageXpress Nano | microscopy | WIP | [OEM](https://www.moleculardevices.com/products/cellular-imaging-systems/high-content-imaging/imagexpress-nano) | | Tecan | Infinite 200 PRO | absorbancefluorescenceluminescence | Mostly | {doc}`PLR <02_analytical/plate-reading/tecan-infinite>` / [OEM](https://lifesciences.tecan.com/plate_readers/infinite_200_pro) | | Tecan | Spark 20M | absorbancefluorescence | Mostly | {doc}`PLR <02_analytical/plate-reading/tecan-spark>` / [OEM](https://lifesciences.tecan.com/multimode-plate-reader) | ### Flow Cytometers | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Beckman Coulter | CytoFLEX S | WIP | [OEM](https://www.beckman.com/flow-cytometry/research-flow-cytometers/cytoflex-s) | ### qPCR Machines | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Thermo Fisher Scientific | QuantStudio 5 | WIP | [OEM](https://www.thermofisher.com/order/catalog/product/A34322) | ### Scales | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Mettler Toledo | WXS205SDU | Full | {doc}`PLR <02_analytical/scales/mettler-toledo-WXS205SDU>` / [OEM](https://www.mt.com/us/en/home/products/Industrial_Weighing_Solutions/high-precision-weigh-sensors/weigh-module-wxs205sdu-15-11121008.html) | ### Barcode Scanners | Manufacturer | Machine | PLR-Support | Links | |--------------|---------|-------------|--------| | Keyence | Barcode Scanner | Full | [OEM](https://www.keyence.com/products/barcode/) | --- ## Understanding the Tables Classifying lab automation equipment can be challenging. There are many reasons for this, including (but not limited to): - many machines have overlapping capabilities (the TFS Cytomat 2 C470 can be a fridge, heated chamber, oven, smart storage/plate hotel and shaker all in one machine!), - different user groups require varying levels of software integration but tend to only refer to the capabilities they use in that moment (e.g. what is a shaker to one group might be a heater to another), - balancing naming/classification based on user intuition/historic legacy and first principles, (e.g. a thermocycler is just a speedy heater/cooler but scientists are used to the term thermocycler) - there is no widely accepted naming standard. PyLabRobot does not solve these human classification issues. But to provide *some* structure PyLabRobot classifies machines into three purposefully broad categories: - **Liquid handling**: Machines directly manipulating liquids. - **Material handling**: Machines handling materials other than liquids. - **Analytical**: Machines primarily responsible for performing measurements. **Table Columns Explained:** - **Features**: Core capabilities provided by the machine. - **PLR-Support**: Indicates PyLabRobot integration status: - **WIP**: Work in progress. - **Basics**: Core functionalities available. Code integrated into `pylabrobot:main`. Documentation pages in `docs.pylabrobot.org`. - **Mostly**: Most capabilities available, but some known commands still missing. - **Full**: Comprehensive capabilities (≥90%) fully supported, extensive documentation available. Note: PyLabRobot aims to provide access to all hardware-firmware capabilities available on integrated equipment, even beyond OEM software. This allows users to *choose* the machine functionalities they require.